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Techno-Blast
Friday, March 2, 2018  |  Volume 10 / Number 4  |  A Production of the BioProcessing Journal
ISBioTech 8th Spring Meeting
PlasmidFactory
Career Development
BOKU
Protein Chromatography Course – Engineering Fundamentals and Measurement for Process Development and Scale-Up
May 27–June 1, 2018
Vienna, Austria
MSS 2018
Monolith Chromatography Summer School and Symposium
June 15–20, 2018
Portorož, Slovenia
HPLC
HPLC 2018
July 29August 2, 2018
Washington, DC USA
Suggested Reading
The Contamination Triangle:
A New Model for Assessing the Risk of Biological
Process Contamination and Performing Investigations
By Bill Ogden, MedImmune
Sponsored Link
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Products & Services
New Host Cell Protein Detection Service
BioPharmaSpec announces the launch of “The BioPharmaSpec Approach” for mass spectrometry (MS)-based detection of host cell proteins (HCPs). The new in-house service allows access to a pre-existing approach that detects a wider population of HCPs than possible with traditional ELISA technologies.

The BioPharmaSpec Approach has the distinct advantage of detecting HCPs in a de novo manner, without specialized polyclonal antibody reagents or product/process-specific method development. BioPharmaSpec apply their renowned MS expertise within a clearly-defined, staged approach, which includes:
The BioPharmaSpec Approach
Qualitative analysis to identify the HCPs present
Quantitation against a response from a known spiked protein
Quantitation of the HCPs against heavy labeled marker peptides
For more information, please visit biopharmaspec.com.
Bioluminescent Imaging Capabilities Accelerate Robust CAR T-Cell Therapy
Crown Bioscience enhances its existing platform for chimeric antigen receptor (CAR) T-cell agent evaluation with bioluminescent imaging capabilities. CAR T-cell therapies are an exciting advent in the evolving field of immune-therapeutics. CAR T-cell agents utilize CAR T-cells that recognize tumor-associated antigens and subsequently promote tumor elimination. The remarkable efficacy of CAR T-cell compounds has led to hundreds of clinical trials with two notable successes recently approved by the FDA to treat refractory B-cell precursor acute lymphoblastic leukemia (ALL).

CrownBio offers a CAR T-cell platform for proof-of-concept and therapeutic efficacy validation. Clinically relevant in vivo and in vitro models combine with a comprehensive suite of analytical services to enable efficient, early evaluation of CAR T-cell agents. The addition of bioluminescence imaging (BLI) for non-invasive evaluation of systemic and orthotopic tumor progression, in real-time, further enhances an already robust platform and provides a unique set of solutions to advance CAR T-cell therapies.

For more information, please visit crownbio.com.
Job Posting
Genethon
Manager Group
"AAV Vector Expression Systems"
Career Development
Human Biotech and Animal Health
Human Biotech & Animal Health Business Partnering Summit
March 12–13, 2018
Boston, Massachusetts USA
ECI
Cell Culture Engineering XVI
May 6–11, 2018
Tampa, Florida USA
Vaccine Technology VII
June 1722, 2018
Mont Tremblant, Quebec, Canada
PREP
PREP 2018—31st International Symposium on Preparative and Process Chromatography
July 8–11, 2018
Baltimore, Maryland USA
The Waterside Conference
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