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Wednesday, June 21, 2017  |  Volume 9 / Number 13  |  A Production of the BioProcessing Journal
Career Development
8th Annual Virginia Viral Pathogenesis Symposium
June 24, 2017
Norfolk, Virginia USA
30th International Symposium on Preparative and Process Chromatography
July 16–19, 2017
Philadelphia, Pennsylvania USA
CMC Strategy Forum Summer
July 17–18, 2017
Gaithersburg, Maryland USA
Mass Spectrometry
September 19–22, 2017
Boston, Massachusetts USA
XXV Anniversary Congress
October 17–20, 2017
Berlin, Germany
ISBioTech 5th Fall Meeting
Suggested Reading
From the Editor-in-Chief: Biologics Logic
By Keith L. Carson, ChE, MBA, BioProcessing Journal
Products & Services
Affordable Digital Imaging and Multi-Mode Detection
BioTek Instruments introduces the Cytation™ 1 Cell Imaging Multi-Mode Reader for automated digital quantitative microscopy along with multi-mode microplate detection. This solution provides quantitative phenotypic cellular information and well-based quantitative data, while the modular architecture satisfies current research needs with additional upgrade modes available to suit future needs.
The digital microscopy mode includes fluorescence and high contrast brightfield channels for visualization from 1.25x to 60x. Additionally, automated XY stage, focus, and LED intensity facilitate imaging throughput, especially during cell-based applications. The multi-mode detection module includes sensitive filter-based fluorescence and luminescence along with monochromator-based UV-Vis absorbance for flexibility in a wide range of endpoint, kinetic, inject/read, and other assay types. Both modules incorporate powerful, user-friendly Gen5™ Microplate Reader and Imager Software.
Cytation™ 1 Cell Imaging Multi-Mode Reader
Cytation 1 also offers 4-Zone™ temperature control, variable shaking modes, CO2/O2 gas control, and angled reagent injectors. Cytation 1 is compatible with a variety of sample vessels, including microplates, slides, cell culture dishes and flasks, hemocytometers, and the Take3™ Micro-Volume Plate. For more information, please visit
Pilot Fermenter for Manufacturing APIs
Bosch has launched a new pilot fermenter for the cultivation of active pharmaceutical ingredients (APIs) at laboratory and pilot scale. Depending on the selected mixer, the fermenter can process batch sizes from 8 or 13 L, up to 50 L. In addition, reactor sizes for 100 and 200 L are available for pilot and small industrial batches. The system can be equipped with one of several interchangeable mixing elements, designed for different cell types and process controls. Feeding of process media is fully automated.
new pilot fermenter
The fermenter supports batch and fed-batch processes, as well as perfusion and continuous processing. Additionally, the system is built as a package unit and the integrated wall allows the clear separation of technical section from operational area. The fermenter is designed for easy cleaning and sterilization (CIP/SIP). Its integrated periphery includes a steam generator, exhaust air cooler, and a heating/cooling device for the bioreactor. Depending on the task-specific requirements, up to four interchangeable process sensors are available to enable quick installation with limited media availability and quick changeover. For more information, please visit
Next-Generation Gel Imaging System
Syngene introduces its NuGenius+ gel imaging system configured with powerful new software for generating accurate, high quality images of stain-free protein gels, in addition to DNA agarose and SDS-PAGE gels.
Featuring a compact darkroom, large UV transilluminator, and UV filter, the NuGenius+ is touch screen controlled by image capture software. NuGenius+ can be automatically set up in seconds to capture images of TGX Stain-Free™ FastCast™ acrylamide gels, Mini-PROTEAN®, and Criterion™ TGX Stain-Free precast gels.

Complete with a high-resolution 5 million pixel camera and integrated Raspberry Pi processor, the NuGenius+ can be fitted with Syngene’s White Light Converter Screen or the new UV-Blue Light Converter Screen. These allow the NuGenius+ to inexpensively detect a range of visual and fluorescent dyes such as Coomassie Blue, GelGreen™ SYBR® Safe, SYBR Gold, and SYPRO® Ruby for precisely visualising protein and DNA on gels. For more information, please visit
NuGenius+ gel imaging system
Career Development
Lewa and Repligen
Pioneering an Approach to Integrated Continuous
June 22, 2017
10:00 AM EDT
13th Conference on Protein Expression in Animal Cells
September 24–28, 2017
Valencia, Spain
BPJ Publishing
BioProcessing Journal Open Access
Techno-Blast Masthead
A possible therapy for macular degeneration is to transplant retinal pigment epithelial (RPE) cells on bioengineered, nanofibrous scaffolds into patients’ eyes. Here a pseudo-colored image of the RPE cells growing out over the nanofibers can be seen. Each cell has thousands of “tongues” and “rods” protruding from its surface that would naturally support rod and cone cells in the eye.

Courtesy of Cellular Dynamics International, a FUJIFILM company.
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