Thursday, June 9, 2016  |  Volume 8 / Number 12  |  A Production of the BioProcessing Journal
ISBioTech 4th Fall Meeting
Career Development
2016 Annual Meeting
June 22–25, 2016
San Francisco, California USA
29th International Symposium
July 17–20, 2016
Philadelphia, Pennsylvania USA
Downstream Processing Course
July 25–29, 2016
Massachusetts USA
ETH Zurich
Short Course:
Continuous Chromatography for Biotherapeutics
September 4–9, 2016
Zürich, Switzerland
Cell and Gene Therapy
ESGCT Annual Meeting
October 18–21, 2016
Florence, Italy
Techno-Blast Masthead
iCell® Cardiomyocytes grown on CYTOO micropatterns for seven days show alignment of sarcomeres organization. (Magnification x40; red: TroponinT, green: α-actinin, blue: nucleus).

Courtesy of Cellular Dynamics International, a FUJIFILM company.
Suggested Reading
Serum: What, When, and Where?
By Rosemary J. Versteegen, PhD, International Serum Industry Association (ISIA)
Sponsored Link
PATfinder™ – Free Lunch Seminar Series
On June 20, please join us for a free lunch seminar on PATfinder™, our rapid, powerful, and highly flexible chromatography system designed for Process Analytical Technology (PAT), which will be held at the Hyatt Regency Cambridge at 575 Memorial Drive, Cambridge, MA 02139, USA.
Production of extremely valuable biological products typically involves complex manufacturing processes with high variability. PAT can be used to enhance process understanding and provide a holistic approach to ensure that quality is built into products — by design. As the process evolves, PAT can therefore incorporate fast and robust analytical techniques which generate high quality information about critical quality attributes. BIA Separations is proud to introduce PATfinder which provides a combination of state-of-the-art PAT high pressure chromatography with monolithic columns, as well as chromatographic data analysis software that enables at-line monitoring of a series of critical quality attributes — simultaneously.

Please RSVP to book your place, since this is a RSVP-only event. In addition, please feel free to forward this invitation to any of your colleagues you think may be interested in attending. This lunch series will take place in:
Cambridge, Massachusetts on June 20th
Chesterfield, Missouri on June 21st
San Diego, California on June 22nd
San Francisco, California on June 24th
Gaithersburg, Maryland on June 27th
For more information, please visit
PATfinder™ HPLC
BIA Separations
Products & Services
Kilo Lab Extension Opened at US Facility
Novasep has finalized the set-up of its new synthesis laboratory and kilo lab at its US facility. Production of kilogram-scale batches of synthetic molecules for biological testing and preclinical trials has begun according to schedule.
The US facility in Boothwyn, Pennsylvania is equipped with jacketed reactors ranging from 100 mL to 50 L in size and with a 35 L filter dryer for isolation of kilogram quantities of compound. The laboratory extension features all the necessary equipment for standard and cryogenic chemistry. In terms of purification services, it provides North American customers with the complete portfolio of Novasep preparative chromatography technologies, such as HPLC (Hipersep®) and SFC (Supersep®). In addition, it has all the required analytical tools for process research and development (HPLC, HPLC/MS, GC, GC Headspace, UPLC, UPLC/MS, etc.), including a calorimetric reactor for preliminary process safety testing.
Novasep Boothwyn
For more information, please visit
Expanded Single-Use Vessel Portfolio for Microbial Fermentation
Eppendorf has expanded its portfolio of rigid-wall single-use vessels for fermentation. The newly launched Eppendorf BioBLU® 3f was developed specifically for microbial bioprocessing in working volumes of 1.25 to 3.75 L, extending the full range of operation for single-use fermentation from 60 mL to 3.75 L.
BioBLUf Eppendorf's line of BioBLU f Single-Use Vessels specifically address the demands of high cell density fermentation of bacteria, yeasts, and fungi. Robust magnetic overhead drives featuring Rushton-type impellers support agitation rates up to 1200 rpm and provide high-performance mass transfer. The exclusive integrated cooling baffles enable efficient heat removal for exothermic processes, while the rigid-wall industrial stirred-tank design ensures scalability and simplifies technology transfer. The monolayer polymer material mitigates risk and uncertainty with regard to leachables and extractables.

BioBLU 3f single-use bioreactors are designed as drop-in replacements for existing autoclavable fermentation vessels. They can be operated with the Eppendorf bioprocess control stations BioFlo® 115, BioFlo 310, and BioFlo 320. For more information, please visit
Career Development
Beckman Coulter
Free Webinar:
DNA & RNA Sequencing Sample Prep: Automating Simple to Complex Methods
June 23, 2016
8:00 AM PT
CMC Strategy Forum
Summer 2016
July 18–19, 2016
Gaithersburg, Maryland USA
Cell & Gene Therapy / Immunotherapy
September 21–22, 2016
Berlin, Germany
9th Annual Bioassay Conference
September 28–30, 2016
Dubrovnik, Croatia
BPJ Publishing
BioProcessing Journal BioProcessing Journal BioProcessing Journal
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