Wednesday, January 20, 2016  |  Volume 8 / Number 2  |  A Production of the BioProcessing Journal
Career Development
CMC Strategy Forum
January 25, 2016
WCBP 2016
January 26–28, 2016
Washington, DC USA
Cell and Gene
Therapy World
January 25–27, 2016
Washington, DC USA
19th Annual Meeting
May 4–7, 2016
Washington, DC USA
29th International Symposium on Preparative and Process Chromatography
July 17–20, 2016
Pennsylvania USA
HPLC 2016
44th International Symposium on High Performance Liquid Phase Separations and Related Techniques
June 19–24, 2016
San Francisco, California USA
Suggested Reading
Coming ‘Round to Spheroid Culture
By Bhaskar S. Mandavilli, PhD, Cindy Neeley, PhD, MaryKay Bates,
and Magnus Persmark, PhD, Thermo Fisher Scientific
Products & Services
MHC Class II Tetramer Reagents to Study Antigen-Specific CD4+ T Cell Immune Responses
ProImmune introduces ProT2™, a range of Human MHC Class II tetramer reagents for tetramer analyses in the study of antigen-specific CD4+ T cell immune responses. ProImmune’s offering represents the broadest choice of ready to order catalog and custom items in this field, and enables research into CD4+ T cell responses in a variety of disease areas including cancer, infectious diseases, allergy, autoimmunity, and transplantation. Another key area is the detailed study of T cell help in unwanted immune responses to biologics. ProT2™
ProT2 MHC Class II tetramers allow the direct detection and separation of single antigen-specific CD4+T cells accurately by flow cytometry. This addition to ProImmune’s Class II reagent offering complements an already extensive range of services for evaluating CD4+ T cell responses, including ProImmune REVEAL® MHC peptide binding assays, CD4+ T cell and DC T cell proliferation assays, and standard immune monitoring services through ELISPOT and flow cytometry based assays.

For more information, please visit
3D Cell Invasion Assay
Oris™ 3D Embedded Invasion Assay
announces the launch of the Oris™ 3D Embedded Invasion Assay — a unique product offering quantifiable real-time analysis of cell invasion. The assay is designed to enable cell movement through an extracellular matrix (ECM) in 3-Dimensions, thereby getting as close as possible to an in vivo experiment using in vitro conditions.
Based upon patented “exclusion zone” technology which uses cells embedded in a collagen matrix — Oris 3D Embedded Invasion Assays from AMSBIO provide a simple, quantitative, and efficient way to monitor cell invasion and morphology changes in a more physiologically relevant microenvironment. With no artificial membranes obscuring visualization of the cells, cell invasion rates and morphology changes can be reproducibly and quantifiably measured as end-point assays or in real-time. Designed in an industry-standard 96-well plate format, the assay can be used with microscopes, plate readers, and high-content imaging systems, thereby delivering significant reductions in handling time for setup and analysis.

For more information, please visit
Latest Bioreactor Control Software
Finesse Solutions has released TruBio® DV version 5.0 control software for both bioreactors and mixers. TruBio DV software can be used with glass vessels, rockers, media or buffer mixers, and most sizes/brands of single-use bioreactors to provide a seamless solution from 0.5 L R&D through 2000 L cGMP-compliant production.

TruBio DV version 5.0 is powered by a DeltaV® Controller from Emerson Process Management and is optimized for DeltaV versions 12 and 13. It is also compatible with the Emerson DeltaV batch platform for cGMP-compliant operation and Syncade-based MES systems.

TruBio DV 5.0 has been enhanced to utilize Finesse's new SmartParts family of intelligent digital actuators to implement off-the-shelf solutions for continuous processing and automated harvest. In addition, the software can be used to create batch recipes for media mixing and/or buffer preparation. TruBio DV 5.0 retains the full capabilities of the "multi-feed" dosing function to deliver low volume feed additive doses with high precision, and allows scalability to large doses into production systems. With its graphical interface improved for consistency, ease of visualization, and enhanced alarming, TruBio DV 5.0 fully supports Finesse Universal Controllers to create a unique and flexible upstream bio-processing solution.

For more information, please visit
TruBio® DV version 5.0 control software
Economize by combining Techno-Blast and BioProcessing Journal advertising into one package.

Don't finalize your media plans without consulting
our media kit!
Email us to request a copy.
Techno-Blast Masthead
An artist's rendering of the retrovirus.

Email your cell images to the editor today!
Career Development
Integrated Training in Development and Clinical Practice of Cell-Based Therapies
Multilevel Characterization of mAbs with ONE Method
February 17, 2016
11:00 AM ET/8:00 AM PT
Emerging Targeted Therapies in Cancer and Autoimmunity
April 21–25, 2016
Varadero, Cuba
Host Cell Protein Workshop
May 17–19, 2016
Lisbon, Portugal
BIA Separations
7th Monolith Summer School and Symposium
May 27–June 1, 2016
Portorož, Slovenia
BPJ Publishing
BioProcessing Journal BioProcessing Journal BioProcessing Journal
Did a colleague forward this to you? Subscribe here. While we'd hate to see you go, you can unsubscribe instantly.