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Thursday, January 7, 2016 | Volume 8 / Number 1 | A Production of the BioProcessing Journal
Career Development
CMC Strategy Forum
January 2016
January 25, 2016
WCBP 2016
January 26–28, 2016
Washington, DC USA
Washington 2016
January 25–27, 2016
Washington, DC USA
ASGCT 19th Annual Meeting
May 4–7, 2016
Washington, DC USA
PREP 2016—29th International Symposium on Preparative and Process Chromatography
July 17–20, 2016
Pennsylvania USA
HPLC 2016
HPLC 2016—44th International Symposium on High Performance Liquid Phase Separations and Related Techniques
June 19–24, 2016
San Francisco, California USA
2016 BIO International Convention
June 6–9, 2016
San Francisco, California USA
Techno-Blast Masthead
Confocal micrograph
of MDCK epithelial cells

Image provided by
Michael W. Davidson,
National High Magnetic
Field Laboratory
FSU Tallahassee

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to the editor today!
Suggested Reading
Next Generation Vaccines:
Development of a Novel Streptococcus pneumoniae Multivalent Protein Vaccine
By Paola Cecchini, Camilo A. Colaco, ImmunoBiology Ltd. (ImmBio), et al.
Sponsored Link
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BioPlan Survey
BioPlan Survey
BioPlan Survey
Products & Services
Automated Imaging and Analysis of 3D Tumor Spheroids, Cancer Stem Cells
The Celigo® S Cell Imaging Cytometer from Nexcelom Bioscience LLC provides high-speed, fully automated imaging and quantification of suspension, adherence cells, tumor spheroids, iPSC, and cancer stem cell colonies. Celigo S is a bench-top, micro-well plate-based, bright field and fluorescent imaging system. It has been used in the development of 3D tumor spheroid-based functional assays for target validation and drug evaluation. S Cell Imaging Cytometer
With Celigo S, suspension cultures of tumor spheres, including mammospheres and neurospheres, can be rapidly and accurately analyzed. This automated morphometric analysis tool significantly reduces the time and effort needed to quantify key aspects of 3D spheres including size, growth, growth tracking over time, and response to chemotherapeutics. Analysis of tumor spheres generated from different cancer cell lines and primary cancer cells can be used to evaluate sphere-forming efficiency, tumorigenicity, and self-renewal of cancer stem/tumor-initiating cells.

With an intuitive software interface and optional integration into automation platforms, the Celigo provides labs with increased capabilities. For more information, please visit
New Micro-Scale Bioreactor System Provides
Enhanced Microbial Strain Screening with Fed-Batch Capability
Sartorius Stedim Biotech (SSB) introduced the new ambr® 15 fermentation system, an automated micro bioreactor system designed to enhance microbial strain screening with advanced capabilities supporting fed-batch microbial cultures.
The new system comprises 24 single-use stirred micro bioreactors (each with an 8–12 mL working volume) integrated to a user-friendly, automated workstation. Parallel processing and walk-away control of 24 micro bioreactors provides efficient, consistent results from an enhanced early-stage screening platform. The system also permits full control of DO and pH in fed-batch culture, impeller stirring, gas sparging, and pumped additions of pH reagent and feed.

ambr systems are widely used for cell line development and process optimisation, and are proven to provide a reliable model and consistent scalability to a range of upstream processes. For more information, please visit
ambr® 15 fermentation system
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Career Development
Integrated Training in Development and Clinical Practice of Cell-Based Therapies
5th Annual Meeting
January 23–27, 2016
San Diego, California USA
Host Cell Protein Workshop
May 17–19, 2016
Lisbon, Portugal
BIA Separations
7th Monolith Summer School and Symposium
May 27–June 1, 2016
Portorož, Slovenia
BPJ Publishing
BioProcessing Journal BioProcessing Journal BioProcessing Journal
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