Wednesday, October 28, 2015  |  Volume 7 / Number 22  |  A Production of the BioProcessing Journal
Career Development
2nd Progress and Challenges in Protein Particles and Immunogenicity of Biotherapeutics 2015:
Filling in the Gaps in Risk Evaluation and Mitigation
November 12–13, 2015
Rockville, Maryland USA
CMC Strategy Forum
Japan 2015
November 9–10, 2015
Tokyo, Japan
WCBP 2016
January 26–28, 2016
Washington, DC USA
Washington 2016
January 25–27, 2016
 Washington, DC USA
ASGCT 19th Annual Meeting
May 4–7, 2016
 Washington, DC USA
Techno-Blast Masthead
A spooktacularly modified image of cardiomyocytes.

Original image courtesy of
Lonza Group, Ltd.
Basel, Switzerland.

Email your cell images to the editor today!
Suggested Reading
Glucagon-Like Peptide 1 Synthesis for Use in Human Diabetes Treatment
By Archana Gangakhedkar and Jyothi Thundimadathil
American Peptide Company
, a member of the Bachem Group
Sponsored Link

Single-Use Clarification Systems for Up to 2,000 Liters
Sartoclear Dynamics® is a new single-use technology for harvesting animal cell cultures with high cell densities. Consistent results, ease of use, enormous speed, and flexible scalability are the key characteristics of this technology. Inspired by the plasma industry, Sartoclear Dynamics is based on the principles of body feed filtration. The ready-to-use clarification system enables single-use processing up to 2,000 liters. As a result, it replaces centrifuges and the subsequent depth filters in a single step.

For more information, please visit

Products & Services
Enhanced Generic E. coli Host Cell Protein (HCP) Assay for Biomanufacturing
BioGenes GmbH has launched a generic HCP assay with improved HCP recovery properties for E. coli cells. The E.coli|360-HCP ELISA allows sponsors and biotech companies to postpone the development of a cost-intensive, specific HCP assay until a more informed decision on the success of a biologic in development can be made.

The assay has been developed using the 360-HCP ELISA approach. While traditional generic HCP assays provide just one single antibody that must work for all processes, the generic 360-HCP ELISA provides several kits, each using a different anti-HCP antibody. An upfront performance test identifies the most suitable ELISA kit.
E.coli|360-HCP ELISA is based on W3110 and BL21 (DE3) cell lines which were fermented in different culture media and temperatures resulting in four antigen preparations with distinct HCP patterns. By immunizing goats with these antigens, BioGenes developed a panel of four different HCP ELISAs that together build up the enhanced generic assay.

For more information, please visit
Uniting Technologies for Method Continuity
Tosoh Bioscience LLC introduces TSKgel UP-SW3000 size exclusion chromatography (SEC) columns. These columns offer dual functionality for use in both UHPLC and HPLC systems and are the latest addition to the renowned TSKgel SW series, the gold standard for QC analysis of antibody therapeutics.
TSKgel UP-SW3000 columns are packed with 2 µm silica-based particles and feature the same pore size as the well-established TSKgel G3000SWXL columns. Hence, methods developed using TSKgel G3000SWXL columns can easily be transferred to TSKgel UP-SW3000 columns on conventional HPLC systems as well as on UHPLC systems. TSKgel UP-SW3000 columns are available in 4.6 mm ID with a 15 or 30 cm length. The 15 cm column offers a shortened analysis time with improved efficiency while the 30 cm column delivers dramatically increased peak parameters such as efficiency, asymmetry, and resolution between fragments, monomers, and aggregates. In addition, the TSKgel UP-SW3000 columns demonstrate superior reproducibility from injection-to-injection and across lot-to-lot and column-to-column.

TSKgel UP-SW3000 columns are now available for sale in the Americas. For more information, please visit
Economize by combining Techno-Blast and BioProcessing Journal advertising into one package.

Don't finalize your media plans without consulting our media kit!
Email us to request a copy.
Career Development
7th Monolith Summer School and Symposium
May 27–June 1, 2016
Portorož, Slovenia
BPJ Publishing

Did a colleague forward this to you? Subscribe here. While we'd hate to see you go, you can unsubscribe instantly.