Friday, October 2, 2015  |  Volume 7 / Number 20  |  A Production of the BioProcessing Journal
Career Development
ISPE Annual Meeting
November 8–11, 2015
Philadelphia, Pennsylvania USA
CMC Strategy Forum
Japan 2015
December 7–8, 2015
Tokyo, Japan
WCBP 2016
January 26–28, 2016
Washington, DC USA
Washington 2016
January 25–27, 2016
 Washington, DC USA
ASGCT 19th Annual Meeting
May 4–7, 2016
 Washington, DC USA
7th Monolith Summer School and Symposium
May 27–June 1, 2016
Portorož, Slovenia
Techno-Blast Masthead
Bovine artery endothelial cells.

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Suggested Reading
Analysis of Downstream Process Controls to Assure the Quality of
Recombinant Granulocyte-Colony Stimulating Factor
By Natacha Pérez, Rodolfo Valdés, PhD, et al.,
Center for Genetic Engineering and Biotechnology (CIGB)
Products & Services
Direct, Real-Time Antibody-Based Virus Quantification
ViroCyt introduces a new paradigm in virus quantification, building upon its award winning Virus Counter® technology.

ViroCyt has developed a novel approach enabling direct, biologically-specific quantification of viruses in minutes rather than the days or weeks required by more traditional approaches. This new product category utilizes a fluorescently-labeled, high-affinity antibody targeted to the virus of interest. ViroTag® reagents are the first designed specifically for baculovirus (ViroTag BCVB) and adenovirus (ViroTag ADVX). During a one-minute sample analysis, the preparation is evaluated with the Virus Counter 3100, an instrument developed expressly for the purpose of real-time virus quantification.

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Automation Compatible 3D Cell Culture Scaffolds
AMSBIO has launched Mimetix® 3D cell culture scaffolds for a range of applications including regenerative medicine, oncology research, drug discovery, and as a unique aligned scaffold for neural growth and investigation.

Compatible with automated handling and imaging equipment, the Mimetix scaffold is incorporated into standard ANSI/SLAS footprint microplate frames with superior optical clarity and minimal base distortion. The scaffold depth of 50 µm is thick enough to provide the benefits of 3D cell culture, yet thin enough to allow fluorescent and light microscopic imaging. Mimetix has been validated with a number of primary cells, cell lines, and stem cells.
Mimetix scaffolds mimic the extracellular matrix by providing an ideal architectural environment to support the growth of cells in 3D, and are free from animal-derived products. In addition to standard formats, AMSBIO offers a custom service to provide different Mimetix scaffold shape, composition, thickness, fibre diameter, and pore size to optimally suit your application. Scaffold customization enables use of biodegradable and regulatory friendly components if desired.

For further information, please visit
System Isolates More Than 10,000 Single Cells Per Day
and Automatically Selects Cells to Process
WaferGen Bio-systems will soon launch the ICELL8™ Single-Cell System. The system sets a new standard for single-cell analysis, enabling unbiased isolation of up to 1,800 single cells on a single chip. The system includes an imaging station for rapid image capture and CellSelect™ software for automatic selection of cells of interest for further processing for RNA sequencing.
ICELL8 provides multi-sample nano-liter dispense technology to accommodate cell sizes from 5–100µm in a single sample. The rapid and simple cell isolation and imaging protocol ensures that multiple chips can be processed in a single 8-hour day. CellSelect software allows for complete user-guided selection, as well as automatic determination of wells with individual cells to select for downstream applications. The system successfully processes various cell types, including live single neurons, human tumor cells, mouse tumor cells and nuclei. The system has also been shown to detect rare cell types with minimal sequencing costs.

The ICELL8 is the first single-cell analysis system to offer the scale of isolation, the control of cell selection, and the openness of study design to truly expand single-cell analysis. For more information, please visit
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Career Development
Recorded Webinar:
Improving Pace and Efficiency of Protein Expression Using Baculovirus Based Systems
HPLC 2016—44th International Symposium on High Performance Liquid Phase Separations and Related Techniques
June 19–24, 2016
San Francisco, California USA
PREP 2016—29th International Symposium on Preparative and Process Chromatography
July 17–20, 2016
Philadelphia, Pennsylvania USA
BPJ Publishing

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