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Wednesday, April 29, 2015  |  Volume 7 / Number 9  |  A Production of the BioProcessing Journal
Career Development
CMC Strategy Forum
Summer 2015
July 20–21, 2015
Gaithersburg, Maryland USA
CMC Strategy Forum
Latin America 2015
August 24–25, 2015
Federal District, Brazil
Immunopharmacology - Vaccipharma 2015
June 14–19, 2015
Varadero Beach, Cuba
Preservation of Molecular, Cellular and Tissue Biospecimens
May 19–20, 2015
Minneapolis, Minnesota USA
Suggested Reading
Continued Process Verification: Monitoring and Maintaining a State of Control
By Kate Lusczakoski, PhD, BIOVIA Science Council
Sponsored Link

When the process is the product, employee competence is your biggest risk.
Make the Biomanufacturing Education and Training Center at WPI an extension of your training program so your team can hone their skills and learn new capabilities in our pilot plant where the processes are real, but product is not at risk.

Working together, we can deliver customized hands-on programs just for your team. Or you can send staff to our open enrollment programs. The goal is to limit the risk of batch failure with skills development, cross-training, error prevention and troubleshooting.

Products & Services
Parasite Vaccines on the Horizon
XstalBio Ltd has commenced work on a €9.3 million EU Funded Horizon 2020 project to develop vaccines that protect cattle, sheep, and poultry against infection by parasites. The four year “PARAGONE” collaboration, coordinated by the Moredun Research Institute, involves 17 partners from Europe, Uruguay, and China and will aim to move several candidate vaccines from the laboratory into practical field trials.

XstalBio, as the formulation and delivery partner, will utilise its proprietary technology to bind antigens and immunostimulants together into vaccine microparticles that function as “inorganic pathogens,” with the aim of improving delivery and obtaining better, more targeted, protection against parasite infections. XstalBio microparticle formulations are thermally stable so any vaccines produced will be suitable for use in developing countries where retention of the cold-chain is challenging.

For more information, please contact Marie Claire Parker or visit
Next Generation Automated Cryogenic Sample Management System
Brooks Automation, Inc. introduces BioStore™ III Cryo, an automated cryogenic sample management system. BioStore III Cryo introduces automation to the largest segment of bio-samples being stored, which currently relies on manual cryo storage systems.

BioStore III Cryo incorporates sample monitoring, tracking, and inventory control with the industry's standard cryo storage vessel. The system can access virtually any type of sample within a cryobox format and retrieve a box of samples in less than 60 seconds. Meanwhile, the other samples stored within the liquid nitrogen system are maintained at a temperature below -135 °C at all times. The highly ergonomic design and built-in user safety features of the BioStore III Cryo system provide new and significant benefits over traditional, manual cryo storage systems.

The new system was developed in collaboration with Chart Industries, the leading provider of manual cryo storage systems. For more information, please visit
Techno-Blast Masthead
HeLa cell spheroids were generated in a Nuclon™ Sphera round-bottom 96-well plates and transferred to
35 mm Nunc glass-bottom dishes. Oxidative stress was measured by using CellROX® Deep Red stain from Molecular Probes® with nuclear counterstaining with NucBlue® Live Cell stain; this sample was treated with 100 µm Menadione for 1 h at 37°C, causing an dramatic oxidative stress response as indicated by the elevated red signal compared to control samples.

Courtesy of Thermo Fisher Scientific.

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Career Development
ASGCT 18th Annual Meeting
May 13–16, 2015
New Orleans, Louisiana USA
PREP 2015—28th International Symposium on Preparative and Process Chromatography
July 26–29, 2015
Philadelphia, Pennsylvania USA
BPJ Publishing

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