Wednesday, March 6, 2013  |  Volume 5/Number 5  |  A Production of the BioProcessing Journal
Career Development
BioDownstream Technologies Course 2013
April 15-19, 2013
Piran, Slovenia
2nd Workshop:
The New ParadIgM – IgM from Bench to Clinic
April 23-24, 2013
Frankfurt, Germany
245th ACS National Meeting
& Exposition
April 7-11, 2013
New Orleans, Louisiana
April 16-18, 2013
Washington, DC Metro Area
Techno-Blast Masthead
Dendritic caps
(confocal micrograph).

Courtesy of Thomas Moninger, Assistant Manager, University of Iowa's Central Microscopy Research Facility,
Used under permission.

Email your cell images
to the editor today!
Suggested Reading
White Paper: Process Analytical Technology (PAT) for Biotech
A Review of Recently Reported Applications in Fermentation and BioProcessing
By Terry P. Redman, Urs Groth, Fabio Visentin, Dominique Hebrault, Ben Smith,
Des O’Grady, and Brian O’Sullivan, METTLER TOLEDO
Sponsored Link
Cell Counting Made Easy
Perfect for large to small scale applications in biopharma, industrial, and academic fields, the Vi-CELL XR Cell Viability Analyzer automates the widely accepted trypan blue dye exclusion method for cell viability that has historically been performed manually with a light microscope, pipette, and a hemacytometer.

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Products & Services
New Size Exclusion HPLC Chromatography Columns
Thermo Fisher Scientific recently introduced the new Acclaim™ SEC-300 and SEC-1000 size exclusion HPLC columns. These columns are designed for high resolution separation of water-soluble polymers and oligomers. They are optimized for determining molecular weight distribution and characterization of water-soluble polymers used in a wide range of products found in pharmaceuticals.

The two columns have differing pore sizes to offer separations over a wide linear range of 100 to 1,000,000 Daltons. Based on a proprietary mono-dispersed multi-pore hydrophilic resin, these columns provide high resolution and good linearity for accurate and reliable analyses. The columns are compatible with a wide range of detectors including: UV, RI, MS, ELSD, and corona-charged aerosol.

For more information, please visit: or
Single-Use TFF Solution for Pre-Clinical to Clinical cGMP Biomanufacturing

has launched the Sius™ single-use tangential flow filtration (TFF) skid, which is the first on the market to offer
a 100% single-use TFF solution.
The Sius TFF skid is comprised of an automated bench-top
unit with a fully disposable flowpath and is extremely compact. It is capable of lab to pilot-scale TFF operations. The unit accommodates surface areas from 0.1 square meters to 2.0 square meters for microfiltration and ultrafiltration/diafiltration (UF/DF) applications, eliminating the risk of cross-contamination.
The Sius TFF skid’s flowpath can be combined with TangenX Sius TFF cassettes and filter plate inserts with the option of a feed bag, to provide a complete single-use TFF solution from a single supplier for pre-clinical to clinical cGMP biomanufacturing. It is also one of the only solutions to enable cGMP validated integrity tests.

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  Career Development
Virginia Regional Herpes Symposium
April 6, 2013
Norfolk, Virginia USA

Partnering for Vaccine Emerging Markets
June 10-12, 2013
Berlin, Germany
23rd ESACT Meeting:
Better Cells
for Better Health
June 23-26, 2013
Lille, France
BPJ Publishing