Wednesday, January 9, 2013  |  Volume 5/Number 1  |  A Production of the BioProcessing Journal

Career Development
January 28-30, 2013
Washington, DC USA
Microbial Fermentation: Development & Scale-Up
March 19-22, 2013
Cell-Based Vaccine Production:
A Hands-on Approach
June 11-14, 2013
Techniques In
Animal Cell Culture
& Scale-Up Strategies
June 11-14, 2013
All courses take place in:
Logan, Utah USA
Participate in the 10th Annual Global Biopharmaceutical Manufacturing Study
April 16-18, 2013
Washington, DC Metro Area
Techno-Blast Masthead
Multinucleate HeLa cell in metaphase. DAPI, anti-bovine a-tubulin, mouse monoclonal 236-10501, biotin-XX conjugate and Alexa Fluor® 568 streptavidin.

Copyright © 2012
Life Technologies Corporation ( Used under permission.

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to the editor today!
Suggested Reading
White Paper: Recent Advances for Seeding a Crystallization Process
By Brian O’Sullivan, Benjamin Smith, and Georgiy Baramidze, Mettler-Toledo AutoChem, Inc.
Publisher's Commentary
As we head into 2013, let’s hope that our industry can settle into its “new normal.” While we can’t expect things to be the way they were in the 1990s, or even the early 2000s, perhaps we’ll land in a realm that is more efficient and makes more sense. We’ve not only gone through the worst economic disaster since the Great Depression, but most biotech organizations... read more >>
Products & Services
Levitating Cells Provides a More Accurate Representation of Tissue In Vivo
Bio-Assembler Kits utilize magnetic levitation to culture cells in 3-D. Available in single, six, and 24-well configurations, the kits supply magnetic drivers, low-binding dishes/plates, and Nanoshuttle-PL solution in quantities and volumes appropriate to kit size.

Nanoshuttle-PL solution delivers magnetic nanoparticles to cells. The magnetic driver that nests on top of the dish/plate then levitates the cells to create a 3-D environment. Using the Bio-Assembler Kits is as easy as performing standard 2-D cell culture plating and propagation.
Culturing cells in 3-D facilitates rapid formation of floating yet connected scaffold-like structures with cell-cell interactions, thus providing a more accurate representation of tissue functionality in vivo. The process is compatible with virtually any cell type, including primary and stem cells, with any media type, with standard culturing protocols and diagnostic techniques, and is applicable to invasion studies and tissue engineering.

Bio-Assembler Kits are available from MIDSCI through an agreement with n3D Biosciences, Inc. and will be offered throughout the United States. For more information, please visit
Reduce Batch Times in Culture Media Production
The Quadro Ytron® ZC Disperser from Quadro Engineering is specifically designed to disperse extremely difficult-to-wet powders into a liquid stream in a single-pass, and can reduce batch times to less than one hour. The vacuum in the reactor housing ensures that powders from the hopper above are drawn into the reactor head, where the particles are subjected to intense mechanical shearing prior to hydration into the liquid stream. The result is a homogeneous dispersion of powders without "fish-eyes" or lumps, and minimal foaming.

The ZC Disperser is designed for clean-in-place and does not require disassembly or an external method for cleaning. With the addition of the Uniform Film Interface (UFI) Feeding System, referred to as the Kontinuum Powder Disperser, the ZC can be converted to operate continuously — 24/7 — at customer-specified powder and liquid incorporation rates.

For more information, please visit
Sustainable Cooling Technologies for High-Performance Buildings
The eVap cooling system from Cannon Design delivers increased energy efficiency, cost savings, and safety by offering direct, point-of-source cooling of equipment and experiments without heating the surrounding laboratory environment.

The eVap1000 utilizes the building’s existing chilled water or process water system to reject the heat from experiments through a highly efficient magnetic bearing pump, and stainless steel metal plate and frame heat exchanger. The eVap 1500 Heat Exchanging Water Cooling Unit cools processes and equipment without using tap water or small air-cooled chiller units with compressors. This not only eliminates the related flood risks associated with using tap water, but saves fresh water as well.

With both models, electrically non-conductive cooling fluid can be circulated safely through electrical equipment to provide superior cooling without the risk of short circuiting the electronics.

For more information, please visit
Follow Us
  Career Development
WCBP 2013:
17th Symposium on the
Interface of Regulatory
and Analytical Sciences
for Biotechnology
Health Products
January 29-31, 2013
Washington, DC USA
5th Annual Biomanufacturing Summit 2013
January 28-30, 2013
San Diego, CA USA
2nd Workshop:
The New ParadIgM – IgM from Bench to Clinic
April 23-24, 2013
Frankfurt, Germany
23rd ESACT Meeting:
Better Cells
for Better Health
June 23-26, 2013
Lille, France
BPJ Publishing
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