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Friday, July 13, 2012  |  Volume 4/Number 14  |  A Production of the BioProcessing Journal

Career Development
Fermentation Technology
July 30-August 3, 2012
Downstream Processing
August 6-10, 2012
Both courses take place in: Cambridge, MA USA
Drug Product for
Biological Medicines:
Novel Delivery Systems, Challenging Formulations and Combination Products
On-Demand Webinar:
3D Cell Culture
in Drug Discovery
and Disease Modeling
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Suggested Reading
Productivity Studies Utilizing Recombinant CHO Cells in Stirred-Tank Bioreactors:
A Comparative Study Between Pitched-Blade and Packed-Bed Bioreactor Systems
By Kamal Rashid, PhD, et al., Utah State University
Protecting the Excipient Supply Chain
By Frithjof Holtz and Najib Sehat, Merck Millipore
From the Publisher: Trip to Slovenia
We were invited to visit Slovenia and cover a monolith chromatography course that BIA Separations holds every two years during the summer. And while I consider myself a reasonably good student of geography, I had to admit that I didn’t know anything about Slovenia, let alone where it was located. I assumed it was part of the former Yugoslavia, and having followed the dissolution of this country in the ‘90s, I assumed it must be a land of great tragedy with thousands of undiscovered land mines and bombed out buildings, plus UN peacekeepers riding around in Humvees.

So I had to ask myself: “What am I getting myself into?” A quick Google search identified a vibrant country of about two million people that was indeed part of the former Yugoslavia, and that it was on the Adriatic Sea with Italy to the west, Austria to the north, Hungary to the northeast, and Croatia to the east and south.
>> read more
Products & Services
Lonza Launches Next Generation GS Gene Expression System™
Lonza has launched the new GS Xceed™ Gene Expression System. The GS Xceed System has been proven to reduce cell line development timelines by up to 6 weeks over the existing CHOK1SV based system and has achieved titers of up to 6 g/L. Companies with protein therapeutics in their pipeline can access this new system, available for use globally in all major pharmaceutical and biotechnology markets.

For more information, please visit
The key element of the new system is the CHOK1SV GS Knock-out host cell line. The complete GS Xceed System includes: cGMP banked CHOK1SV GS-KO host cells, GS expression vectors, full protocols, access to Lonza’s latest Commercial Platform Production Process (chemically defined, animal component-free media and feeds system), and access to Lonza’s GS technical team.
BioWelder® TC: Fully Automated Device for Welding Large and Liquid-Filled TPE Tubing
Sartorius Stedim Biotech has launched the BioWelder® Total Containment (TC). BioWelder TC, featuring innovative technology, permits sterile connection of liquid-filled thermoplastic tubing that has an outer diameter (OD) of up to 1 inch and that is used on disposable bags or bag assemblies in all biopharmaceutical manufacturing processes.

The sterile welding process is fully automated and can be performed in nonclassified or classified environments while maintaining product sterility. The thermal weld produced by BioWelder TC ensures an extraordinary level of stability, thus guaranteeing an ultra-safe connection. The thermal weld has been qualified by applying the most stringent and innovative test regimes. Biological, physical, and extractables tests were combined to obtain data representing a variety of process conditions, including critical applications.

For more information, please visit
GENEWIZ RNA-Seq: Making Sense of Your Sequence Analysis
GENEWIZ RNA-Seq service (whole transcriptome shotgun sequencing) offers complete solutions from library construction through bioinformatics data analysis and data storage. Upon completion of RNA-Seq projects, all data is accessible online and available for download via a three-month Simbiot® single user license.
GENEWIZ has the ability to analyze over 100 species including any genome from: Ensembl; EnsemblMetazoa; EnsemblPlants; EnsemblFungi; EnsemblProtist; and EnsemblBacteria. In addition, GENEWIZ can analyze any genome listed with NCBI, as well as any genome starting from private, draft, or partial sequences.

For more information, please visit
or email

  Career Development
Control of Bioburden
in Biotech Processes
July 31, 2012
11:00 AM-12:30 PM
Downstream Processing of Biotechnology Products
September 11-14, 2012
Microbial Fermentation: Development & Scale-Up
October 16-19, 2012
Cell-Based Vaccine Production:
A Hands-on Approach

November 13-16, 2012
All courses take place in:
Logan, Utah USA
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Techno-Blast Masthead
A culture of
Madin-Darby Canine Kidney (MDCK) epithelial cells.

Image provided by
Michael W. Davidson,
National High Magnetic
Field Laboratory
The Florida State University, Tallahassee.

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