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Thursday, April 19, 2012  |  Volume 4/Number 8  |  A Production of the BioProcessing Journal

Career Development
Combining Nucleation Technology and Aseptic Processing: The Impact
on the Viability
and Performance
of Process Simulation Media Fills

Free Webinar
April 24, 2012
9:00 AM and 2:00 PM EST
Phacilitate Immunotherapy Leaders' Forum 2012
May 9-11, 2012
Barcelona, Spain
PerkinElmer Owners Group
June 6-8, 2012
Newton, Massachusetts

Techno-Blast Masthead
Breast Cancer Cell

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Wrap-Up for the 2012 ISBioTech Annual Meeting
This year our annual meeting was held the first week of April in a Rosslyn, Virginia high-rise office building located just across the Potomac River from Washington, DC. The 24th floor facility offered state-of-the-art conference rooms, as well as floor to ceiling windows that gave us a panoramic view of Georgetown and the nation’s capital.

We featured three program tracks on the applications that are currently most important to our members: baculovirus expression technology, viral vectors and vaccines, and antibodies and recombinant proteins. And in my humble opinion, the talks were the best we’ve ever presented, with a major focus on vaccines involving antigens, virus-like particles, and viral vectors. Then among the viral vector talks, the most attention was concentrated on retroviruses, AAV, and lentiviruses; but adenovirus and other virus types appear to be gaining renewed interest...

>> Click here to read more.
Products & Services
Biotage® Unveils Isolera™ Spektra with Full PDA Spectral Scanning
Biotage® introduces the new, Isolera™ Spektra to expand the scope of application of its flash chromatography product line by increasing efficiency with significant solvent and time saving capabilities as well as enabling purity assessment technology.

The new full PDA spectral scanning capability with λ-All detection and baseline correction generates real-time PDA spectral data for eluting compounds. This provides compound detection at any wavelength, enabling chemists to see how pure their eluting compounds are in both real-time and post-purification. Post-purification spectral analysis can also be conducted in both two- and three-dimensional displays for improved visibility of impurities and eliminating the need for post-flash TLC purity testing.

The new proprietary TLC-to-Step gradient feature instantly converts TLC separation data into an efficient step gradient and suggests a sample load for up to six compounds. Chemists can target one or more compounds for isolation, dramatically reducing solvent requirements and purification time compared to linear gradients.

For more information, please visit
Redesigned FLT Vial Filler – Now With 100% Checkweigh Option
Bosch Packaging Technology presents its redesigned FLT vial filler. Due to its small size and flexibility, the FLT is ideal for clinical trials and small batches. The scaled down FLT allows manufacturers to replicate the conditions of higher speed production, thereby anticipating potential variables.
The latest version requires minimal size parts and impresses with a small footprint and reduced changeover times. The new design also improves on flexibility and simplicity in the first stage of drug development. Stoppering or capping of 13 and 20 mm finish is realized with a single vibratory bowl, requiring only the change of tracks. Spring-discs ensure robust and efficient capping. Rotating crimp roller technology is now standard on the FLT filler which handles containers ranging from 2 to 100 mL and processes up to 30 vials per minute.

100% checkweigh and a new reject station account for automated, precise dosing and dose weight verification. Peristaltic or rolling diaphragm pumps are used for filling, either with re-usable or single-use PreVAS product path parts. For more information, please visit
Student-Proof Heating Block System
Developed in response to widespread demand, Asynt has introduced a new version of its popular DrySyn heating block system for teaching and academic research laboratories. The DrySyn Scholar brings together robust, low cost, enhanced operator safety features and ease of use.

Specifically designed for safety conscious teaching laboratories — the DrySyn Scholar enables single 100 mL or 250 mL round bottom flask reactions to be performed safely without the mess or inherent hazards of a hot oil bath or heating mantle. Prominent permanently fixed lifting handles ensure moving is easy, fast, and safe — even with hot reaction blocks. Compatible with almost any magnetic hotplate stirrer, the low thermal mass design of the DrySyn Scholar minimises both power consumption and reaction heat-up time.

For more information, or to request a product demonstration, please visit
  Career Development
Monolith Summer School and Symposium
June 1-6, 2012
Ajdovščina, Portorož, Slovenia
Microbial Fermentation: Development & Scale-Up
May 22-25, 2012
Gene Expression &
Microarray Analysis

June 18-20, 2012
Downstream Processing of Biotechnology Products
September 11-14, 2012
All courses take place in:
Logan, Utah USA
BPJ Publishing
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