Premier Issue of the Techno-Blast
The Source of BioProcess Efficiency
Filtration, Separation,
and Purification Solutions
News from Vivante
Career Development


We will do our best to post announcements for the most valuable training courses, networking opportunities, and job openings. Please help us build this portion of the site by sending us your event and job postings


Protein Purification Courses


3-Day Hands-On Instruction
In Downstream Processing

Practical Applications
of Metabolomics

Half-Day Regional Workshop

Cell Culture Engineering XII

Call for Abstracts

Cell Culture Seminar Series

Scientific Seminar Series
Co-Hosted By ATCC and SIVB



We will be posting valuable information from key technology supply firms. As with our other primary content, these postings will have been assessed for their balance and credibility, and will include application data, tutorials, articles, presentations, and case histories.

Then in our Supplier-Side column, we will post materials with clear commercial content such as infomercials, ads, press releases and promotions. And while some of these will be sponsored postings, other valuable resources will appear with no strings attached.



Adenovirus Reference Material
Source Needed for Long-Term Stability Testing

The Adenovirus Reference Material (ARM, ATCC VR-1516) is a wild-type human type 5 adenovirus that is available internationally as a reference material. It was last tested for long-term stability at month 74, in October 2007. In order to continue to collect data on the stability of this important resource, the ARM Working Group is soliciting donations of testing services, specifically the determination of vector particle concentration and infectious titer. Testing will recur every two years as long as the donor is still willing to donate this service.

Characterization and Qualification of
Cell Substrates for Manufacturing
Viral Vaccines in the United States

By Arifa S. Khan, PhD
(, is Senior Investigator in the Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, US Food and Drug Administration, Bethesda, Maryland.

Testing Strategies for Mammalian Cell Banks

By Michelle Quertinmont
(, James Moldenhauer, and Dayue Chen, PhD; Eli Lilly and Company, Indianapolis, Indiana.


Functionally-Improved Recombinant Antibodies: Moving Toward Higher Levels of Expression

By Christian Kranz, PhD, ( is Product Manager, Directed Evolution; Michael Liss, PhD, is Senior Scientist, Directed Evolution; Frank Notka, PhD, is Manager of R&D; Michael Spring, PhD, is Product Manager, Gene Delivery; and Ralf Wagner, PhD, is CEO, CSO; Geneart AG, Regensburg, Germany.

Peptide Synthesis in Pharmaceutical Manufacturing

By Gary Hu ( is Vice President of Sales and Marketing with American Peptide Company, 777 East Evelyn Ave., Sunnyvale, CA 94086 USA; Phone: (408) 733-7604.

Genotyping Without DNA Isolation
DirectPCR® Lysis System Allows Direct Genomic PCR


Please submit materials via email to, but be sure to zip the file if it exceeds 2 MB.  Another option is to mail us the file on a key drive, but note that we won’t return your drive since we collect them and it isn’t worth the handling cost.  And then, you can upload the file to your FTP site and send us the URL and password we’ll need to download it.  Or you can simply email us a link so we can view the material on another website.  Depending on the content and format of the material, we will post links to wherever it can best be viewed or downloaded.   

All submissions must address a recent advancement or solidify a “best practice” for biologic product development or production. The material format can be streaming video, YouTube postings, automated PowerPoint presentations; as well as PDF, HTML, Word and Excel docs. Be sure to include complete contact information for the corresponding submitter, an introduction of no more than 75 words, and a list of key words.


If you would like to help review submissions for a specific application or technology area, please contact Include your full contact information, the area(s) in which you would like to contribute, and any relevant experience you’ve had on a review or advisory board.


Please contact to get a quote for advertising or for sponsoring our efforts.


We hope you enjoy visiting our site and find the content both valuable and timely. We are committed to posting the best technical content we can collect as we do our best to make your interaction a pleasurable experience. We look forward to reading your comments at


Headlines and links will take you to various postings on our site, and when appropriate, to the sites of various contributors. Postings will include articles, presentations, assays, techniques, protocols, blog chat, reviewer comments, product tutorials, virtual tours, application data, and pretty much any other form of online material that’s needed to develop and produce safe and effective products.


Our initial focus will be on the toughest applications which tend to receive very little coverage elsewhere, such as viral gene vectors and cellular products. But as things progress and interest is expressed, we’ll be adding Development Groups to cover applications such as vaccines, antibodies, recombinant proteins, and tissue regeneration.

Each technology and application will have its own Development Group with one or more Reviewers and numerous contributors.

Development Groups
  • Viral Vectors
  • Cellular Products
  • Safety and Efficacy
  • Cell Banking
  • Vaccines
  • Antibodies and Recombinant
  • Facilities
  • Quality Systems

Technologies will include essentially all the unit operations and support functions involved in bioprocessing, such as cell engineering and banking, cell culture scale-up, filtration, purification, media development, assay development, regulatory affairs, and facility design.


Content formats will include streaming video, YouTube postings, automated PowerPoint presentations; and of course PDF, HTML, Word, and Excel docs.