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Techno-Blast
Thursday, April 13, 2017  |  Volume 9 / Number 8  |  A Production of the BioProcessing Journal
ISBioTech 5th Fall Meeting
Career Development
International Serum Industry Association
12th Annual Meeting
May 3–4, 2017
Hong Kong
CASSS
Bioassays 2017:
Scientific Approaches & Regulatory Strategies
May 8–9, 2017
Silver Spring, Maryland USA
CMC Strategy Forum Europe 2017
May 22–24, 2017
Killarney, Ireland
ASGCT
20th Annual Meeting
May 10–13, 2017
Washington, DC USA
25th ESACT Meeting
25th ESACT Meeting
May 14–17, 2017
Lausanne, Switzerland
PREP
30th International Symposium on Preparative and Process Chromatography
July 16–19, 2017
Philadelphia, Pennsylvania USA
ISBioTech 8th Spring Meeting
Suggested Reading
From the Editor-in-Chief:
Exciting Things are Happening in the Biotech Industry
By Keith L. Carson, ChE, MBA, BioProcessing Journal
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Products & Services
New Cell Line Development Service

ATUM (formerly DNA2.0) has expanded its services to include cell line development, enabled by its proprietary Leap-In Transposase® genome engineering tools.

ATUM has also begun construction of a new, 7000 SF mammalian cell engineering laboratory at its Newark, California headquarters.  The new facility, slated to be fully operational by September 2017, will double ATUM's lab space dedicated to mammalian work, and will include a cGMP cell bank manufacturing facility that is expected to be fully validated by the end of the year.

ATUM has discovered, characterized, and patented two new families of transposases engineered using its ProteinGPS technology for complex genome engineering of mammalian cells, including the rapid generation of high-titer protein expression lines. The technology enables any recombinant DNA sequence to behave as a transposon — a mobile genetic element — and to efficiently transpose the cargo from delivery vectors to target cell chromosomes via a "cut & paste" mechanism. The Leap-In Transposase rapidly catalyzes the stable, quasi-random integration of many copies of a transposon into the target genome. Transposases integrate the entire transposon every time and thus produce more stable and higher producing lines, and greatly reduce the downstream screening burden.

For more information, please visit atum.bio.

pH Electrode for Hygienic and Sterile Applications

Endress+Hauser introduces Memosens CPS171D pH electrodes for use in bioreactors, fermenters, and other hygienic and sterile applications. The CPS171D measures 0–14 pH and operates in temperatures from 32–284 °F (0–140 °C), making it suitable for clean-in-place (CIP) and sterilize-in-place (SIP) operations up to 284 °F (140 °C).

The CPS171D pH probe has been developed with a unique reference gel and glass membrane. These new features improve the long-term stability for reliable and accurate measurement, even after multiple CIP and SIP cycles. The CPS171D is IECEx and ATEX approved for use in hazardous locations; has IP68 protection and a TÜV certificate; and has FDA, USP, and ISO approvals for biocompatibility regarding cytotoxicity and bioreactivity.
Memosens CPS171D pH electrodes
Memosens technology allows the sensor to store measuring and operating data. Recording sensor data in the sensor itself enables predictive maintenance and makes it easy for asset management software, such as Memobase Plus, to facilitate life-cycle management. For more information, please visit us.endress.com.
New Inverted Microscope Platform for Life Science Research

ZEISS introduces the Axio Observer family, consisting of three stable and modular microscope stands for flexible and efficient imaging, reproducible results, and high quality image data.

The Axio Observer combines the proven quality of ZEISS optics with new automation features, allowing multimodal imaging of living and fixed specimens. Among these features is Autocorr, a technology that permits adaption of immersion objectives to varying sample carriers and imaging conditions, and an Autoimmersion option that builds up and maintains stable water immersion. Definite Focus.2 is a novel hardware focus that automatically compensates for focus drift and enables long-term time-lapse imaging and demanding multi-position experiments.

Axio Observer
The Axio Observer platform is controlled by ZEN imaging software. The current 2.3 release integrates all new features seamlessly and offers convenient experiment setup with dedicated wizards, large-data acquisition, and data processing in 2D and 3D. ZEN supports open interfaces and scripting, thus allowing setup and integration, even into complex lab workflows. Experimental data can easily be exported to a multitude of file formats and third-party software.

For more information, please visit zeiss.com
Career Development
ISPPP
ISPPP 2017
July 19–21, 2017
Philadelphia, Pennsylvania USA
PEACe
13th Conference on Protein Expression in Animal Cells
September 24–28, 2017
Valencia, Spain
BPJ Publishing
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