Wednesday, July 8, 2015  |  Volume 7 / Number 14  |  A Production of the BioProcessing Journal
Career Development
Career Opportunity
Laramie, Wyoming USA
New Presentation:
Improving the Pace and Efficiency of Protein Expression Using Baculovirus-Based Systems
CMC Strategy Forum
Summer 2015
July 20–21, 2015
Gaithersburg, Maryland USA
CMC Strategy Forum
Latin America 2015
August 24–25, 2015
Brasília, Federal District, Brazil
PREP 2015—28th International Symposium on Preparative and Process Chromatography
July 26–29, 2015
Philadelphia, Pennsylvania USA
Techno-Blast Masthead
Fibroblast Cells

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Suggested Reading
Upward Trends in BioTech
By Keith L. Carson, BioProcessing Journal
SUPPLIER SIDE:
Streamline Your Cell Line Screening:
With the Automated, Microscale, Stirred Tank, Single-Use Bioreactor
By Tim Ward, TAP Biosystems, part of the Sartorius Stedim Biotech Group
Products & Services
2000 Liter Single-Use Bioreactor
EMD Millipore, the Life Science business of Merck KGaA, has introduced the Mobius® 2000 L single-use bioreactor. This newest bioreactor to join Mobius' stirred tank bioreactor portfolio (3, 50, and 200 L) provides the ultimate in flexibility, scalability, and convenience by incorporating industry-leading design features to enable easy optimization of the upstream process.

Features new to the 2000 L bioreactor include the industry's first pull-out drawer and self-deploying bag. With this design, no hoisting is required during Flexware® assembly installation and removal, making installation and inflation safe and easy while minimizing operator intervention. An external SensorReady loop connected to the Flexware assembly enables additional sensors to be incorporated without modifying the assembly, and while still assuring sterile connections.

The Mobius 2000 L single-use bioreactor can be supplied as a fully-integrated system with intuitive GMP-compliant software, allowing easy integration into plant automation strategies. For customers with plant-wide common automation strategies, the bioreactor can be integrated into third party automation platforms. For more information, please visit emdmillipore.com/MobiusTwist.
Highly Scalable, High-Throughput Flow Cytometry-Based Screening Solution
Genedata and IntelliCyt have announced a technology alliance to transform screening of suspension cells. The alliance integrates the highly scalable data analytics and workflow capabilities of Genedata Screener® software with the high-throughput flow cytometry capabilities of the IntelliCyt iQue® Screener system to enable efficient screening of large libraries against suspension cells and multiplex beads in phenotypic drug discovery, antibody screening, immunology, and biomarker research.
The iQue Screener is an integrated instrument, software, and reagent system that enables rapid, high content, multiplexed analysis of cells and beads in suspension in industry standard 96-, 384-, or 1536-well plates. The system allows analysis of more than 10,000 cells or beads per second, each with 6–15 parameters. Over 36,000 low-volume, plate-based samples (1 µL samples are typical) can be tested per day. Genedata Screener imports well results, as well as raw and pre-gated cell data, from iQue Screener and supports the fast and efficient processing of routine screening.

For more information, please visit intellicyt.com and genedata.com.
High Performance Multi-Mode Microplate Reader
BioTek has released the new Synergy™ Neo2 Multi-Mode Reader, an advanced, high-performance, high-speed plate reader with improved performance and new features.

Synergy Neo2 incorporates BioTek’s patented Hybrid Technology™ with its independent optical paths to ensure uncompromised performance. Continuously variable bandwidth quadruple monochromators, sensitive high transmission filter-based optics, and up to four photomultiplier tubes (PMTs) provide ultra-fast measurements with excellent results.

Advanced environmental controls, including CO2/O2 control, incubation to 65°C, and variable shaking support live cell assays. Meanwhile, cell-based detection is optimized with direct bottom illumination. Barcode-labeled filter cubes help streamline workflows and limit errors, and the available BioStackNeo plate stacker can be integrated for high-throughput requirements. Powerful Gen5™ Data Analysis Software is included, and features designed for 21 CFR Part 11 compliance are available in Gen5 Secure.

For more information, please visit biotek.com.
Career Development
ISPPP 2015—35th Symposium and Exhibit on the Separation and Characterization of Biologically Important Molecules
July 29–31, 2015
Philadelphia, Pennsylvania USA
BPJ Publishing






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