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Wednesday, June 24, 2015  |  Volume 7 / Number 13  |  A Production of the BioProcessing Journal
Career Development
CMC Strategy Forum
Summer 2015
July 20–21, 2015
Gaithersburg, Maryland USA
PREP 2015—28th International Symposium on Preparative and Process Chromatography
July 26–29, 2015
Philadelphia, Pennsylvania USA
Techno-Blast Masthead
Confocal micrograph of Madin-Darby canine kidney epithelial cells (MDCK).

Courtesy of Michael W. Davidson, National High Magnetic Field Laboratory (www.microscopy.fsu.edu), The Florida State University, Tallahassee. Used under permission.

Email your cell images to the editor today!
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Suggested Reading
Two-Step Purification of Antibody from Tobacco Plants for Vaccine Manufacturing:
Aqueous Two-Phase Extraction and Affinity Chromatography
By Williams Ferro, Rodolfo Valdés, PhD, et al.,
Center for Genetic Engineering and Biotechnology (CIGB), Havana, Cuba
Sponsored Link

Single-Use Clarification Systems for Up to 2,000 Liters
Sartoclear Dynamics® is a new single-use technology for harvesting animal cell cultures with high cell densities. Consistent results, ease of use, enormous speed, and flexible scalability are the key characteristics of this technology. Inspired by the plasma industry, Sartoclear Dynamics is based on the principles of body feed filtration. The ready-to-use clarification system enables single-use processing up to 2,000 liters. As a result, it replaces centrifuges and the subsequent depth filters in a single step.

For more information, please visit sartorius.com.

Products & Services
Next-Generation Biochromatography Equipment
for Protein Purification in Batch and Continuous Modes
Novasep announces the launch of BioSC® Lab, the next-generation of low pressure chromatography equipment for the biopharmaceutical industry. With BioSC Lab, scientists can purify a few grams of proteins per day either in continuous, batch, or even parallel batch modes.

Its simulation software, BioSC Predict, frees the process developer to set the most efficient mode and parameters to purify biomolecules such as monoclonal antibodies (mAbs), blood factors, and other proteins.

What makes BioSC Lab unique is its flexibility in process operating modes. It is specifically designed to quickly provide the operator with the best operating parameters for purifying and converting a batch biochromatography method into a continuous, optimized one.

BioSC Lab is the first in a line of next-generation chromatography equipment that Novasep will introduce to the market over the next few years. For more information, please visit novasep.com.
Automated Hemagglutination Analysis System for Improved Vaccine Characterization


For more information,
please visit indevr.com.
InDevR, Inc. has launched the Cypher One™ system, an affordable instrument and software package that automates the interpretation of hemagglutination (HA) and hemagglutination inhibition (HI) assays.

Until now, interpretation of HA and HI assays required specialized expertise to accurately read and manually record the data, with experienced users often differing in their interpretation of the titer value. The Cypher One system not only standardizes analysis and eliminates subjectivity, but also provides a digital, traceable record to enhance data quality and reliability.
Development of the Cypher One system was funded in part by a National Institutes of Health two-year Phase 1 Small Business Innovation Research grant sponsored by the National Institute of Allergy and Infectious Diseases (R43 AI106054). The first commercial units are slated to ship in September of this year.
Career Development
ISPPP 2015—35th Symposium and Exhibit on the Separation and Characterization of Biologically Important Molecules
July 29–31, 2015
Philadelphia, Pennsylvania USA
BPJ Publishing






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