Wednesday, June 10, 2015  |  Volume 7 / Number 12  |  A Production of the BioProcessing Journal
Career Development
CMC Strategy Forum
Summer 2015
July 20–21, 2015
Gaithersburg, Maryland USA
PREP 2015—28th International Symposium on Preparative and Process Chromatography
July 26–29, 2015
Philadelphia, Pennsylvania USA
Techno-Blast Masthead
Bronchial epithelial cells (confocal micrograph).

Courtesy of Thomas Moninger, Assistant Manager, University of Iowa's Central Microscopy Research Facility. Used under permission.

Email your cell images to the editor today!
Suggested Reading
TECHNOLOGY REVIEW:
Successful High Density Escherichia coli Fermentation Using
the Eppendorf BioFlo® 320 Advanced Bioprocess Control System
By Bin Li, PhD, and Ma Sha, PhD, Eppendorf, Inc.
Sponsored Link
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Products & Services
Ready-to-Use Tagged cDNA Clones
Now available from AMSBIO are TrueORF®cDNA clones for protein studies. The TrueORF product line is a new generation of cDNA clone products that enables expression of the encoded transcript as a tagged protein. This facilitates multiple downstream applications that utilize an anti-tag antibody (Myc-DDK or GFP) including protein detection, protein purification, subcellular localization, and others.

TrueORFs not only provide an instant solution for tagged protein expression, but also offer the flexibility of being shuttled into multiple destination vectors. TrueORF cDNA clones have verified and guaranteed insert sequences, and have been rigorously tested for expression of the target proteins and their tags.
AMSBIO is able to offer genome-wide coverage from its greater than 33,000 human, 25,000 mouse, and 15,000 rat full-length validated cDNA clones. Provided as 10 µg transfection-ready plasmids and driven by CMV promoters, TrueORF cDNA clones produce authentic transcripts without PCR artifacts. For more information, please visit amsbio.com.
Novel Silicon Chip Rapidly Identifies Small Molecules in Biofluids
Protea Biosciences Group, Inc. has announced a new silicon chip technology, REDIchip™, that enables the rapid identification and quantitation of small molecules in biofluids. REDIchip (Resonance-Enhanced Desorption Ionization) employs a patented, nanopost array (NAPA) nanotechnology invented in the laboratory of Prof. Akos Vertes, PhD, Department of Chemistry, The George Washington University, and exclusively licensed to Protea.

REDIchip was developed by Protea in conjunction with a $14 million DARPA cooperative research agreement led by The George Washington University, and included GE Global Research and SRI International. The project's goal is to develop new tools to elucidate the mechanism of action of a threat agent, drug, biologic, or chemical on living cells within 30 days of exposure in order to enhance and support the development of effective threat mitigations and countermeasures.

REDIchip is formatted as a disposable, single-use, 96-well target plate suitable for simple and complex biological mixtures, and compatible with most standard MALDI-MS instrumentation. For more information, please visit proteabio.com.
Career Development
Immunopharmacology - Vaccipharma 2015
June 14–19, 2015
Varadero Beach, Cuba
ISPPP 2015—35th Symposium and Exhibit on the Separation and Characterization of Biologically Important Molecules
July 29–31, 2015
Philadelphia, Pennsylvania USA
BPJ Publishing
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