Wednesday, September 3, 2014  |  Volume 6 / Number 18  |  A Production of the BioProcessing Journal
Career Development
PDA/FDA Joint
Regulatory Conference
September 8–10, 2014
Washington, DC USA
Annual BEBPA
Bioassay Meeting
September 24–26, 2014
Barcelona, Spain
ISPPP—34th International Symposium on the Separation of Proteins, Peptides and Polynucleotides
November 5–7, 2014
Würzburg, Germany
Techno-Blast Masthead
A549 cells
(confocal micrograph).

Courtesy of Thomas Moninger, Assistant Manager, University of Iowa's Central Microscopy Research Facility, cmrf.research.uiowa.edu. Used under permission.

Email your cell images to the editor today!
Suggested Reading
Optimising Vaccine Process Scale-Up of Attachment-Dependent Cells
Using Micro Bioreactors and Microcarriers
By Barney Zoro, PhD, TAP Biosystems, part of the Sartorius Stedim Biotech Group
Discuss on LinkedIn
Risk Assessment of Residual Genomic DNA in Therapeutic Proteins
Using Gene Copy Number Application
By Rahul Fadnis, PhD, Reena Nr, and Rajeev Soni, PhD, Biocon Research Ltd.
Discuss on LinkedIn
Products & Services
High-Quality Genomic DNA from a Single Cell
GE Healthcare Life Sciences introduces the new illustra Single Cell GenomiPhi DNA amplification kit. Delivering higher genome coverage with fewer mutations than PCR-based whole-genome amplification methods, this product enables a more accurate representation of the original genome for increased confidence in results.

The amplification kit combines the unique capabilities of Phi29 DNA polymerase with an optimized formulation to amplify genomic DNA from 1–1000 cells without background interference. Additional features include: a novel clean-up process to suppress background, allowing sensitivity down to 1 femtogram (fg) of input DNA; simple isothermal strand displacement (multiple displacement amplification [MDA]) technology using Phi29 DNA polymerase; 2–4 hour amplification times with hands-on times of 15 minutes or less; and the kit is optimized for complete cell lysis with uniform denaturation of DNA prior to amplification.


For more information, please visit gelifesciences.com.
Versatile Range of Horizontal Gel Electrophoresis Units
Cleaver Scientific's MultiSUB™ horizontal gel electrophoresis systems include a comprehensive choice of optimized units for low- and high-throughput DNA and RNA applications. Designed by scientists for scientists, MultiSUB units provide easy-to-use, versatile, and flexible systems that can evolve and adapt along with the changing needs of today’s laboratory researcher.
All MultiSUB units deliver an unsurpassed combination of gel and buffer volume economy along with gel size and sample number versatility. Gel size and sample number requirements can be exactly matched in each unit with the option of additional gel tray sizes. Easy to use, leak proof "plug and go" gel casting dams are included with each unit, and allow rapid gel casting while the MultiSUB unit is in use for gel running.

For more information, please visit cleaverscientific.com.
Easy-to-Use, Quantitative Gamma-H2AX Assay
AMSBIO announces the first commercially available gamma-H2AX pharmacodynamic assay kit. Gamma- H2AX is a phosphorylated histone historically proven to be a highly specific and sensitive molecular marker for double-strand DNA damage detection. This new assay has been developed for anti-cancer drug screening, basic research, and upcoming clinical trials, providing one of many needed tools to support hypothesis-driven drug design strategies. A white paper describing the use of this product can be downloaded here.

AMSBIO's new 96-well, non-radioactive ELISA assay documents differences in gamma-H2AX levels in peripheral blood mononuclear cells, cultured cells, and tissue biopsies, and is available as a complete reagent kit with chemiluminescent detection.


For more information, please visit amsbio.com.
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Career Development
CMC Strategy Forum
Japan 2014
December 8–9, 2014
Tokyo, Japan
The 27th Annual Meeting of the Japanese Association for Animal Cell Technology (JAACT2014)
November 11–14, 2014
Fukuoka, Japan
BPJ Publishing