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Wednesday, March 5, 2014  |  Volume 6 / Number 5  |  A Production of the BioProcessing Journal
Career Development
Live Webinar:
Using Microbioreactors to Mimic Perfusion Cultures
March 12, 2014
12:00 PM EDT
Bioassays 2014:
Scientific Approaches and Regulatory Strategies
March 24–25, 2014
Silver Spring, Maryland USA
Foundation Symposium of PACT (Platform for Advanced Cellular Therapies)
April 3–4, 2014
Vienna, Austria
6th Monolith Summer School & Symposium
May 30–June 4, 2014
Portorož, Slovenia
Techno-Blast Masthead
HeLa cells were
transduced with CellLight® Mitochondria-GFP, BacMam 2.0 (green) and grown overnight. Cells were imaged on the EVOS® FL Auto imaging system using a 100X objective after nuclear counter-staining with NucBlue® Live cell stain.

Courtesy of
Thermo Fisher Scientific
.
Suggested Reading
Biosimilars in the Rest of the World: Developments in Lesser-Regulated Countries
By Ronald A. Rader, BioPlan Associates, Inc.
Products & Services
Benchtop Automated Sample Decapping, Recapping, and Identification
Hamilton Storage Technologies has launched the LabElite™ line of benchtop devices, offering laboratories an easy and efficient way to automatically process and track samples while ensuring sample integrity. LabElite devices quickly process all common labware types. Three models are available.

The all-in-one LabElite I.D. Capper™ enables labs to combine decapping/recapping and high-speed barcode reading within one device without any additional user interaction. The I.D. Capper is designed to reduce sample contamination and assist with sample tracking during end-to-end, automated liquid handling processing.
The LabElite DeCapper™ decaps and recaps tubes in 48-cryovial or 96-microtube racks. Racks can be automatically moved from portrait to landscape formats for process efficiency. An innovative "secure mode" provides sample security by decapping and recapping only one row at a time, minimizing the time a tube is open, and the rows can be paused for "point-of-use" pipetting.

The LabElite I.D. Reader™ decodes 2D barcoded tubes in all common 12-, 24-, 48-, 96-, and 384-tube racks including honeycomb-shaped racks. The reader can also identify racks with a 2D barcode on the bottom. High-speed decoding algorithms and parallel processing provide fast run times. Optional 1D barcode reading is available.

For more information, please visit hamilton-storage.com
Catalogue of In Vitro Human Tissue Assays
Biopta Ltd, the human tissue-based contract research organisation, has announced a major development in discovery research with the launch of the first catalogue of assays based on human functional tissues. The catalogue serves to provide the scientific community with ready access to assays that improve the prediction of safety, absorption, and efficacy of drug candidates in humans.

Ex vivo
human tissue studies play a key part in drug development, providing pharmaceutical and biotechnology companies with a more predictive human model earlier in the development process. Many pharmaceutical and biotechnology companies have, up until now, depended solely on animal models. However, Biopta’s access to fresh functional human biomaterials means that early human tissue testing is increasingly becoming a routine part of preclinical drug discovery.

Biopta’s research has generated a database of over 60 assays in a range of human fresh tissues. Biopta’s database is the first to build an in vitro library of human functional pharmacology using intact tissues.

Biopta aims to fill the knowledge gap in preclinical testing by providing phenotypically-accurate assays that measure drug responses from healthy and diseased human tissue. For more information, please visit biopta.com
Vibration-Free Chilling Incubators
Torrey Pines Scientific has added to their EchoTherm™ line of incubators with the IN50 and IN55 models. Because they have no compressors or CFCs, these vibration-free, benchtop chilling incubators are ideal for life science laboratory uses including protein crystallography. The new EchoTherm incubators have a 100 L capacity and are Peltier-based for heating and chilling.

The IN50 is simple digital and the IN55 is fully programmable. They are settable from 4.0—70.0°C and feature a proportional-integral-derivative controller (PID) temperature control to ± 0.1°C, a digital display to 0.1°C, and accuracy to ± 0.2°C. Both units have an RS232 I/O port for remote control and data collection, a digital timer (in hours, minutes, and seconds) with a user-settable auto-off, and audible alarms. The IN55 allows for programmable temperature ramping.

The chamber size for the two models is 24" H x 20" D x 14" W, and the incubators come with eight stainless steel split racks (to accommodate a variety of sample sizes) with room for 12. The units are shipped with universal power supplies that take AC line inputs from 100 VAC to 265 VAC, 50/60 Hz, and converts into 12 volts DC for the unit.

For more information, please visit torreypinesscientific.com.
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Career Development
Partnering for Biologic Emerging Markets
May 28–29, 2014
Amsterdam, The Netherlands
ISBioTech 2nd Fall Meeting
October 27–29, 2014
Rosslyn, Virginia USA
BPJ Publishing





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