Friday, October 18, 2013  |  Volume 5 / Number 21  |  A Production of the BioProcessing Journal
Career Development
CMC Strategy Forum
Japan 2013
December 9-10, 2013
Tokyo, Japan
CMC Strategy Forum
& WCBP 2014
January 27-30, 2014
Washington, DC USA
Washington BioLeaders Forum
27-29 January 2014
Washington, DC USA
Molecular Methods for Contaminant and Impurity Assessment Symposium
October 29, 2013
Raleigh, NC USA
Techno-Blast Masthead
Expression of two genes
(confocal micrograph).

Courtesy of Thomas Moninger, Assistant Manager, University of Iowa's Central Microscopy Research Facility, www.uiowa.edu/~cmrf/.
Used under permission.

Email your cell images
to the editor today!
Suggested Reading
Investigation of Light Isomerization of Tropolone Using Liquid Chromatography
and Orbitrap Mass Spectrometry
By Robert J. Duff, PhD and John L. Snyder, PhD,
eurofins Lancaster Laboratories
Sponsored Link
Cell Counting for Academia


Offer ends December 13, 2013.
Vi-CELL is For Laboratory Use Only.
Not for use in diagnostic procedures.
The Vi-CELL XR is a highly accurate and easy-to-use automated cell viability analyzer used by thousands of biotechnology professionals worldwide. To make this technology available to academia, Beckman Coulter is offering a substantial discount to life sciences institutions.

Key features of the Vi-CELL XR include:
  • 12-position auto sampler
  • Concentration range: 50,000 to 10,000,000 cells per mL
  • Customizable cell types which allow analysis of many cell species
  • Minimum sample volume of 0.5 mL
To learn more about the Vi-CELL XR and this special offer,
please visit: www.Vi-CELL.com/academic.



Products & Services
Dual 0.2 µm Membrane Sterilization Filter Cartridge


For more information, please visit porvairfiltration.com.
Porvair Filtration Group has introduced its Hydrofil HTZ dual 0.2 µm membrane sterilization filter cartridge that incorporates a pharmaceutical grade, positively charged Nylon 6,6 membrane. The positive zeta-potential of the nylon membrane enables effective reduction of most endotoxins derived from bacteria, which typically have a negative charge in water. The dual membrane design results in a significant increase in the endotoxin adsorption capacity of the filter.

Applications for Hydrofil HTZ filters include GMP pharmaceutical grade water systems where endotoxin levels need to be kept below Limulus Amebocyte Lysate (LAL) assay detection limits, and endotoxin removal from parenteral products. Filter component materials are approved by the FDA, and meet the United States Pharmacopeia Class VI standards.
Gene-Editing Platform
Horizon Discovery has announced licensing agreements with Harvard University for a Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) gene-editing technology, and Sigma-Aldrich for use of its CompoZr® zinc finger nuclease (ZFN) technology. CRISPR, an RNA-guided gene-editing system, is useful for introducing either a targeted double strand break or single strand nick in the genome of mammalian cells.
Zinc fingers are transcription factors with each finger module recognizing a three to four base gene sequence. The CRISPR and ZFN are available in Horizon’s GENESIS™ recombinant adeno-associated virus (rAAV) technology gene-editing platform. This platform offers researchers a toolbox capable of performing rapid functional genomics and creating high-precision human disease models. Horizon plans to launch a range of rAAV, CRISPR, and hybrid rAAV/CRISPR gene-editing kits and associated reagents.

For more information, please visit horizondiscovery.com.
Advertising
Click on these links to view our Techno-Blast ad specifications and positioning guide.

Economize by combining Techno-Blast and BioProcessing Journal advertising into one package.
Request a quote today.

Don't finalize your media plans for 2014 without consulting our media kit!
Email us to request a copy.
Career Development
6th Annual Biomanufacturing Summit 2014
January 29-31, 2014
San Diego, CA USA
BPJ Publishing